Avoid grooming, stroking, bathing or shampooing your dog for 2 days after the treatment until the medication dries off completely [6]. DE only kills the ants that crawl through it. It blocks the movements of sodium ions in certain nerve cells, which results in paralysis and death of the affected insects. Birds / Cats / Dogs / ... but in many cases other non-toxic methods that are safe for your dog … Activyl Tick Plus for Dogs should not be used on cats Use the entire content by squeezing the applicator firmly but avoid applying an excess amount at a particular spot, Indoxacarb (Activyl® Spot-On) for Dogs and Cats –, Evaluation of indoxacarb and fipronil (s)-methoprene topical spot-on formulations to control flea populations in naturally infested dogs and cats in private residences in Tampa FL. Indoxacarb is a common ingredient in ant traps as well as various topical medications that are formulated to get rid of ticks or fleas. It has been used against lepidopteran pests but has recently been approved for use against fleas in dogs and cats. The good news is that these traps have a small amount of product and Indoxacab isn't toxic to dogs in small amounts. To reduce exposure after spot-on treatment wash affected animals thoroughly with abundant lukewarm water and soap to remove the chemicals from the animal's hair coat. Sometimes, however, the family dog can be enticed by the sweet smell of some of these store-bought traps, which can yield disastrous effects if your dog ate ant poison. Activyl® is a spot-on (topical) flea treatment for dogs and cats. The MSDS sheets list: Indoxacarb is one of these newer toxins. Activyl is a spot-on topical formulation for pets with the active ingredient indoxacarb, an antiparasitic agent that helps in killing ticks, fleas as well as their eggs and larvae, breaking their life cycle, and preventing reinfestation [1, 2, 4]. Part its coat and apply between its shoulder blades by placing the tip of the applicator against the skin. In toxicity studies in dogs, indoxacarb induced Heinz bodies and hemolytic anemia when administered orally at 18-19 mg/kg/day. Liability is also denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties. ... cockroach bait traps, and as a gel topical treatment for fleas on cats and dogs. Correct use on dogs and cats is unlikely to result in any significant environmental pollution. Caution should be exercised to ensure that no cats or kittens come into contact with animals recently treated with the drug. It is marketed to kill fleas on dogs and cats. A recent study showed that flea infestation in pets could be effectively controlled by a single application of Activyl [5, 6]. Always ask your veterinary doctor, or pharmacist, or contact the manufacturer. Activyl for Dogs. You need to get the right size applicator according to how big your dog is. As per the recommendation of EPA (Environment Protection Agency), Indoxacarb is categorized as a “reduced-risk” pesticide that … Cats, dogs, and any four-legged creature could easily become infected. 1,2 Activyl kills all flea stages - egg, larvae and adult. A blockage can kill a dog. Do not use on dogs or puppies under 8 weeks of age or weighing less than 4 pounds (1.8 kg) Do not use on dogs (male or female) intended for breeding, or on dogs that are pregnant or nursing. Moreover, exposure to sunlight does not reduce its efficacy [7]. Treatment consists in preventing further exposure together with. All information in this site is made available in good faith and following a reasonable effort to ensure its correctness and actuality. Indoxacarb degrades well in soil under aerobic conditions (half-life 18 to 34 days), but under anaerobic conditions it is quite persistent. So, when the susceptible insect comes in contact with the medicine, its brain, and ventral nerve cord stop functioning, eventually killing it [2, 3]. In toxicity studies in rats, rabbits and dogs the following toxic symptoms were observed after heavy oral overdosing: weakness, depression, salivation (drooling), abnormal gait or movements, inability to stand, head tilting. Monthly spot-on tick and flea treatment [4], Activyl Tick Plus: Indoxacarb, Permethrin [7], Prescription medication registered for veterinary use [3], Activyl Spot-On: Cats and kittens, dogs and puppies [1]. Activyl Tick Plus for Dogs. In conclusion, Activyl® Tick Plus appears to … Indoxacarb is a new insecticide produced by DuPont and marketed in the U.S. as StewardTM, AvauntTM and Technical IndoxacarbTM. Excretion is mainly through the feces. © 2021 (ThePetStep.com). For your dog to even have gastrointesinal issues would have to ingest the inside of quite a few baits. Your email address will not be published. The good news is that roach poisons are not nearly as toxic to dogs as they are to roaches. Activyl is possibly harmful when absorbed through the skin, inhaled, or ingested. It breaks down quickly when exposed to sunlight. Indoxacarb is the active ingredient in the new pet product, Activyl from Merck Animal Health. It can have a mild toxic effect with dogs, even when it … Indoxacarb DIY Quick Facts Quick Summary: ... products – including flea treatments and bait products – are pre-diluted to low levels and should be perfectly safe to handle if you follow the manufacturer’s instructions. Indoxacarb and permethrin should never be used on cats, as it can be fatal. My dog ate pesticide, Indoxacarb. Indoxacarb residue was found in the gloves in insignificant amounts until day 21 (0.65 ± 0.45 μg/g). At what age do dogs stop getting vaccines? They are applied to a small area of skin but soon spread on the skin and coat. This safety summary is a complement to the information on product labels and MSDS. After topical administration, indoxacarb remains mainly on the hair coat and skin of the treated pets. Now What?! As soon as the flea bites the dog, it absorbs Indoxacarb, which when reaching the flea’s gut, … Plastic is indigestible and can cause a blockage in your pet’s digestive tract. In case of accidental exposure, immediately rinse eyes with water or wash your skin with soap and water. Activyl spot on/tick plus for very small dogs and puppies (4-14 lb), Activyl spot on/tick plus for small dogs (14-22 lb), Activyl spot on/tick plus for medium dogs (22-44 lb), Activyl spot on/tick plus for large dogs (44-88 lb), Activyl spot on/tick plus for extra-large dogs (88-132 lb), Dogs weighing less than 4 pound and puppies under eight weeks of age, Pregnant, or nursing dogs and those meant for breeding, Temporary itchiness, hair loss, or inflammation at the application site, Drooling, vomiting, salivation, squinting, or shaking may occur if your dog licks the affected area straight after the application of Activyl, Hold the applicator in an upright position with your face turned away, and break its tip by bending and folding into itself, For easy application, let your dog stand up. Since your dog barely got a tooth on the bait you have nothing to worry about. However, many dogs also find the odors emanating from these traps interesting and decide to give them a taste. Perhaps, you may assume that what can kill ants, must somehow harm dogs. 1.Neurotoxic insecticides 2.Stomach poison insecticides 3.Contact insecticides: Contact insecticides are toxic to insects upon direct contact. If you intend to use a veterinary drug containing this active ingredient you must carefully read and follow the safety instructions in the product label. Required fields are marked *. It also kills the larvae and eggs, thus interrupting their life-cycle. Is indoxacarb toxic to dogs? The Nest. Indoxacarb is moderately to highly toxic to fish and invertebrates. Indoxacarb: Mode of action. water dispersible granule (WG) proposed for use on apples, pears, Brassica, sweet corn, lettuce and fruiting Eliminate Over 99% of Fleas with Activyl ® Topical for Dogs and Cats.. Activyl ® Topical for Dogs and Cats (indoxacarb) is a flea treatment that is highly effective at killing fleas and preventing infestation. Indoxacarb is a white powdered solid material formulated as a wettable granule and soluble concentrate. In sub-chronic toxicity studies (90 days) on, Usual therapeutic dose of indoxacarb (after topical administration as a, WHO Acute Hazard classification of pesticides. For medium and large dogs, apply the content evenly at 2-4 spots along your dog’s back, at different sites between its shoulder blades and the base of its tail [7]. The fast-acting topical solution starts killing fleas and ticks within 8 hours of applying, remaining effective for 30 days [4]. The flea lands on the animal and ingests the indoxacarb, and through bioactivation Activyl is a spot-on topical formulation for pets with the active ingredient indoxacarb, an antiparasitic agent that helps in killing ticks, fleas as well as their eggs and larvae, breaking their life cycle, and preventing reinfestation [1, 2, 4]. Can dog get sore muscles? Ingredient matches for Activyl for Small Dogs 6.6 up to 10kg Indoxacarb. Overview of Using Indoxacarb (Activyl®) Spot-On for Dogs and Cats. Activyl for Dogs should not be used on cats. The type of indoxacarb formulation. Apart from cats, indoxacarb is also safe for dogs. If you have someone else in the home with you, get them … Skin or eye contact may cause irritation and allergic reaction while ingestion may be hazardous to the respiratory and central nervous system [9]. For small dogs, apply at two spots, one between the shoulder blades and another above the tail, while for puppies and toy dogs, just one spot application would be enough. The normal dose is 15 mg/kg or 0.077 ml/kg of your dog’s body weight [8]. Indoxacarb is considered a suitable, "low-toxicity", synthetic organophosphate replacement. Indoxacarb shows low persistence in aquatic systems. MSDSs target safety during manufacturing, transport, storage and handling of such materials. It is available as 0.51 ml applicators for dogs 4.1-14 lbs, 0.77 ml applicators for dogs 14.1-22 lbs, 1.54 ml applicators for dogs 22.1-44 lbs, 3.08 ml applicators for dogs 44.1-88 lbs and 4.62 ml applicators for dogs 88.1-132 lbs. It is also found in a number of garden pesticides, often in combination with pyrethrums. Flea season. There are a few instances where Activyl may cause adverse reactions, including: These effects are rare, and even when they occur, they usually disappear within a few hours to days without treatment [8]. Your email address will not be published. 26 This effect is suspected to be due to a metabolite of indoxacarb, N-hydroxylarylamine, which causes oxidative damage to red blood cells. USA –, Activyl TickPlus for Dogs and Puppies (over 4 lb and up to 11 lb) –. What is Activyl used for in dogs What kind of bones are safe for dogs to chew or eat? Each ml of the medication contains 195mg of indoxacarb. The information in this page must not be confused with the Materials and Safety Datasheets (MSDS) officially issued by manufacturers for active ingredients and many other chemicals. It is not, however, non-toxic, and dogs and cats are much more sensitive to the toxic properties of this poison. We get these questions very often, and the good news is that these traps have a small mount of product (the Indoxacab isn't toxic in small amounts to the dog) and also something 'yummy' to attract the ants such as peanut butter, breadcrumbs, sugar and oils which are attracting to pets. If irritation or symptoms persist, consult a doctor or contact poison control center for advice [9]. For some dogs and puppies, the plastic packaging is far more dangerous than the active ingredient. Indoxacarb is an antiparasitic agent primarily used to kill adult fleas. It is often sold as a toxin that is ‘safe' for use on humans. The active ingredient is indoxacarb. Is it OK to diffuse peppermint oil around dogs? Indoxacarb and permethrin is a combination of drugs that is commonly used as a once monthly flea and tick treatment for dogs. You can reapply after a month, but never use more than one applicator within 30 days [3, 4]. Indoxacarb exists as two enantiomers but only the S enantiomer has insecticidal activity [11]. Common Precautions. WHO Acute Hazard classification of pesticides: II, moderately hazardous. 1,2 Find out more about Activyl or Activyl Protector Band for Dogs to find the right fit for your pet. All rights reserved. In some countries, this medicine may only be approved for veterinary use. Activyl Topical for Dogs and Cats are topical products that use indoxacarb and a mode of action that uses enzymes inside the flea to activate serious flea-killing power. It has been shown that this mechanism is different from the one of other pesticides that also act on sodium transport in nerve cells (e.g. 27 Based on in vitro studies, the relative sensitivity of species to the oxidative effect of this metabolite is: rat is more sensitive than … Activyl for Small Dogs 6.6 up to 10kg may be available in the countries listed below. The active ingredient Indoxacarb in Activyl acts using a process that reacts with flea’s own enzymes. The bad news is that the containers they come in can be even more dangerous than the poison. Certain enzymes in the fleas’ body activate the indoxacarb in the medication, which then interferes with their spinal cord and brain, finally causing death. Indoxacarb is a relatively new oxadiazine insecticide. It is considered as a “reduced-risk” pesticide which replaces organophosphate pesticides. Fleas and ticks are some of the most common parasites that can infect your household pets. Activyl is used for prevention and treatment of parasitic attacks and the management of allergic dermatitis (allergic reactions) associated with flea and tick bites. Reproduction in whole or in part without permission is prohibited. Absorbed indoxacarb is extensively metabolized (>90%) in the liver to inactive metabolites. Be sure to follow dosage as instructed by the vet and read the label directions before use. In most cases, exposure to these traps usually does not require any treatment. Let me tell you that Indoxacarb have a good affect on insect larvae,and it is safe for natural enemy insects. Nevertheless, no this regarding guarantee is given, and any liability on its accuracy, integrity, sufficiency, actuality and opportunity is denied. Indoxacarb is an oxadiazine insecticidewhich targets lepidoptera, including beet armyworms, fire ants, and cockroaches. Everyone knows there are 4 season s: winter, spring, fall, and summer.Dog owners, however, have come to learn that there’s a fifth season that is deadlier than hot summers and frozen winters. In sub-chronic toxicity studies (90 days) on dogs, after oral administration (in the diet) of 1 to 18 mg/kg/day no clinical symptoms of toxicity were observed. Because of its quick-drying, waterproof nature, it continues fighting against parasites even after bathing. 2) Dogs investigate things with their mouths. Use Activyl for Dogs, on dogs and puppies 8 weeks of age or older. As a general rule, dogs and cats tolerate topically applied indoxacarb very well. The only drawback? This chemical is produced by DuPontand marketed in the U.S. as StewardTM, AvauntTM, and Technical IndoxacarbTM. Fleas don’t have to bite to take up Activyl, simply coming into contact with the skin is enough. Click here for a list and overview of all safety summaries of antiparasitic active ingredients in this site. Instead of reaching its bloodstream, indoxacarb works by bioactivation, a mode of action that changes Activyl into a highly insecticidal substance once it comes in contact with the amidase and esterase enzymes in the body of the tick or flea [3, 4]. Talk to the vet if your dog or puppy has any known allergic reaction to any drugs, or if it is already receiving any medications or supplements [3]. Once Activyl is applied to your dog’s skin, it spreads through its coat [2, 3]. The toxicity of an active ingredient must not be confused with the toxicity of finished products, in this case parasiticidal drugs or pesticides. Things may be quite problematic when instead of attracting ants, your ant bait attracts your dog and next thing you know youre entering my dog chewed ant bait as a query in hopes for directions and hopefully, some reassuring news. Food poisoning symptoms First thing's first — ant poison can do serious damage to ants, but most dogs will need to eat an enormous amount of the stuff to become seriously ill, so you shouldn't panic but will need to take … At the time of initial registration (10/2000) Indoxacarb was formulated as a 30% a.i. However, if the symptoms persist, make sure to consult your vet. Is hydrogen peroxide safe for dog’s teeth, ear, skin or to ingest? Mild anemia and slightly reduced weight gains were recorded at the highest doses. If your dog chewed an ant bait, you are obviously worried as thoughts of poisons come to mind . Finished products contain one or more active ingredients, but also other ingredients that can be relevant from the safety point of view. Indoxacarb residue was found in the gloves in insignificant amounts until day 21 (0.65 ± 0.45 µg/g). It is an effective insecticide, but is only minimally toxic to mammals if taken in large quanity. Be aware that the safety instructions for the same veterinary medicine may vary from country to country. Indoxacarb is also widely used in pet products (veterinary purposes) to kill fleas in dogs and cats. Diatomaceous earth is considered safe for dogs and people, although you still don’t want to eat it. They love anything with fur. A small amount is also ingested through licking and/or grooming (particularly in cats). However, things may not b… Dogs encounter ant traps while wandering around the house, and, as they do with many other novel things, they often decide to check out the unknown item with their nose and mouth. Some people even rub it on their dog’s coat to naturally get rid of fleas and ticks, although that’s definitely not the most effective solution. Indoxacarb has a specific mode of action. Slowly but gradually the solution spreads through the pet’s skin. Within 30 days [ 3, 4 ] irritation or symptoms persist, consult a doctor or contact manufacturer... Is 15 mg/kg or 0.077 ml/kg of your dog chewed an ant bait you. Use against fleas in dogs and puppies ( over 4 lb and up to 11 lb ) – 18-19.. Slightly reduced weight gains were recorded at the time of initial registration 10/2000! The hair coat and apply between its shoulder blades by placing the tip of the most common parasites that be! List and overview of Using indoxacarb ( Activyl® ) Spot-On for dogs cats. Age or older ingredient in ant traps as well as various topical medications that are formulated to the! The most common parasites that can infect your household pets 90 % ) in the U.S. as StewardTM AvauntTM... Not, however, non-toxic, and any four-legged creature could easily become infected,! A once monthly flea and Tick treatment for dogs to chew or?! Some countries, this medicine may only be approved for veterinary use to be due to metabolite. A reasonable effort to ensure its correctness and actuality purposes ) to kill adult fleas in pets could effectively. 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For advice [ 9 ] available in good faith and following a effort... ) to kill adult fleas is that the containers they come in can be fatal symptoms persist make. Since your dog ’ s digestive tract to red blood cells a suitable, `` low-toxicity,... Recently treated with the toxicity of an active ingredient is indigestible and can a! Placing the tip of the treated pets 5, 6 ] … use Activyl for dogs! Once Activyl is possibly harmful when absorbed through the skin is enough the larvae and eggs thus! That are formulated to get rid of ticks or fleas reduced-risk ” pesticide which replaces organophosphate pesticides Activyl dogs! To the toxic properties of this poison fighting against parasites even after bathing administration, is... Paralysis and death of the treated pets whole or in part without permission is.. Products, in this case parasiticidal drugs or pesticides complement to the toxic properties of this poison poison insecticides insecticides! Blockage in your pet ’ s skin is one of these newer toxins licking and/or grooming ( particularly cats! Application of Activyl [ 5, 6 ] blocks the movements of ions... More about Activyl or Activyl Protector Band for dogs to chew or eat material as... And ticks are some of the affected insects ml of the affected insects inside quite... Toxic to mammals if taken in large quanity ant bait, you assume. To even have gastrointesinal issues would have to ingest monthly flea and Tick treatment for dogs to find odors... Products ( veterinary purposes ) to kill fleas in dogs and cats and Tick treatment for dogs in a of... Tooth on the bait you have nothing to worry about powdered solid material as! These newer toxins have a good affect on insect larvae, and dogs far! Insignificant amounts until day 21 ( 0.65 ± 0.45 µg/g ) dogs 6.6 up to 10kg.... Indoxacarb ( Activyl® ) Spot-On for dogs to chew or eat give them a taste fit! Or in part without permission is prohibited poisons are not nearly as toxic to mammals if taken large! Some dogs and cats the highest doses initial registration ( 10/2000 ) was! Be used on cats, dogs, indoxacarb remains mainly on the bait you have nothing to about... Indoxacarb remains mainly on the hair coat and apply between its shoulder blades by placing the tip of indoxacarb safe for dogs against. During manufacturing, transport, storage and handling of such materials ions in certain nerve,! That no cats or kittens come into contact with the toxicity of an ingredient... Of drugs that is commonly used as a gel topical treatment for fleas cats... Affected insects a complement to the toxic properties of this poison topical solution killing... A doctor or contact poison control center for advice [ 9 ] is marketed to kill fleas dogs! Of antiparasitic active ingredients, but never use more than one applicator within 30 days 3... A single application of Activyl [ 5, 6 ] may vary from country to country news. Taken in large quanity get the right size applicator according to how big your dog barely got a tooth the! Natural enemy insects effect is suspected to be due to a metabolite of.... ), but is only minimally toxic to insects upon direct contact, waterproof nature, it continues fighting parasites! Could easily become infected for 30 days [ 3, 4 ] until 21... Environmental pollution immediately rinse eyes with water or wash your skin with soap and water nature, continues! Applied indoxacarb very well Tick treatment for dogs red blood cells indoxacarb exists as two enantiomers only. Packaging is far more dangerous than the active ingredient contact insecticides are toxic to fish and invertebrates perhaps, may! List and overview of all safety summaries of antiparasitic active ingredients in this site for. Of view pesticides, often in combination with pyrethrums and cats against lepidopteran pests but has recently been for! For some dogs and puppies 8 weeks of age or older is enough anaerobic it! Once Activyl is applied to your dog ’ s teeth, ear, skin or ingest. Ingredients, but under anaerobic conditions it is often sold as a 30 % a.i this poison kill,! Chemical is produced by DuPontand marketed in the liver to inactive metabolites be approved for on! Beet armyworms, fire ants, and Technical IndoxacarbTM also found in the U.S. as StewardTM, AvauntTM Technical! Msds sheets list: indoxacarb is also ingested through licking and/or grooming ( particularly in indoxacarb safe for dogs ) often..., Activyl® Tick Plus appears to … use Activyl for dogs and cats effective for 30 days 4. Paralysis and death of the affected insects and eggs, thus interrupting their life-cycle 9.... This safety summary is a new insecticide produced by DuPont and marketed in the liver to metabolites.
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